• The Ocean’s Genome

    After helping to sequence the human genome more than twenty years ago, biochemist Craig Venter seemed to recede from the public eye. But he hadn’t retired. He had gone to sea and taken his revolutionary sequencing tools with him. We chatted with him about his multi-year voyage aboard the research vessel Sorcerer II, its parallels…

    The Ocean’s Genome
  • Light, the Universe, and Everything

    What’s it all about? And we mean ALL. What makes up this vast sprawling cosmos? Why does it exist? Why do we exist? Why is there something rather than nothing? Ow, my head hurts! For possible answers, we travel to the moment after the Big Bang and discover all that… Listen ⇢

    Light, the Universe, and Everything
  • We’ve Got You Made

    Wish you could ditch computers? There’s no escape button for that. Computers are not only a part of your daily grind, they may soon be a part of you. We’ll hear from the world’s first cyborg about why we should make nice in our arms race with machines. Also, the… Listen ⇢

    We've Got You Made
  • Skeptic Check: Superstition

    Wait! Before you step outside… is it Friday the 13th? Any black cats prowling around? Broken a mirror lately? Homo sapiens are a superstitious lot. Find out why our brains are wired for irrational belief. Plus, from the 2012-end-of-the-world prophesy to colliding planets – why some people believe the universe… Listen ⇢

    Skeptic Check: Superstition
  • Bug Off!

    What you can’t see … can make you sick. Humans have been battling viruses and bacteria since the beginning of time. The malaria parasite has been keeping deadly company with us for 500,000 years. King Tut had it and so did Julius Caesar. What’s keeping this bug going today? Also,… Listen ⇢

    Bug Off!
  • What’s Your Poison?

    “Aspirin and Old Lace?” Okay, it would take a bottle full of pills in a glass of elderberry wine to really harm you, but aspirin can be deadly. So can too much of anything, including water. Dose is key in toxicology, after all, but there are some poisons that can… Listen ⇢

    BiPiSci - What's Your Poison
  • Rend Me Your Ears

    Shh – can you keep it down? Nope. Not unless you want to do away with civilization. Our buzzing, humming, whirling, machine-driven world is a poster child for technological progress, right? As is hearing loss. It’s driven one man to search the world for silence. We’ll hear what he didn’t… Listen ⇢

    Rend Me Your Ears
  • Home Brew Science

    The recipe for being a scientist was easy in the old days… just be born into a rich family, have an interest in nature and plenty of time to indulge yourself. But are the days of gentlemen scientists over? Maybe not. We go to the Maker Faire and check out… Listen ⇢

    Home Brew Science
  • Swarm in Here… or Is It Just Me?

    An ant … can’t … move a rubber tree plant… but the colony can. As a group, ants are an efficient, organized, can-do bunch. And a model for humans trying to manage complex systems. Find out about the eerie collective intelligence of animals, and how an MIT researcher is hoping… Listen ⇢

    Swarm in Here... or Is It Just Me?
  • Written in Code

    Genes – what are they good for? Absolutely… something. But not everything. Your “genius” genes need to be turned on – and your environment determines that. Find out how to unleash your inner-Einstein, and what scientists learned from studying the famous physicist’s brain. Also, the bizarre notion that your children… Listen ⇢

    Written in Code

2026 Webby Award Nominee
for our three part series on the 20th anniversary of Hurricane Katrina

Big Picture Science is an immersive radio show and podcast that reveals the unexpected connections in science.

Our Skeptic Check episodes take a critical look at extraordinary science claims and pseudoscience.

Don’t settle for a science snapshot. Get the big picture. 

Hosted By

Molly Bentley Executive Producer and Co-Host, Big Picture Science  

Seth Shostak Producer and Co-Host, Big Picture Science
Senior Astronomer, SETI Institute

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