The biotech tool CRISPR lets us do more than shuffle genes. Researchers have embedded an animated GIF into a living organism’s DNA, proving that the molecule is a great repository for information. This has encouraged speculation that DNA could be used by aliens to send messages. 

Meanwhile, nature has seized on this powerful storage system in surprising ways. Scientists have learned that the 98% of our genome – once dismissed as “junk” – contains valuable genetic treasure. Find out what project ENCODE is learning about the “dark genome.”

Plus, how viruses became the original stealth coders, inserting their DNA into ancient bacteria and eventually leading to the development of CRISPR technology. Discover the potential of this powerful tool, from curing disease to making pig organs transplant-friendly, and the possible dark side of quick-and-easy gene editing.  

Guests:

  • Paul Davies – Director of the Beyond Center for Fundamental Concepts in Science at Arizona State University

  • Yin ShenAssistant professor, Department of Neurology, Institute for Human Genetics, University of California , San Francisco, member of ENCODE team 

  • Sam SternbergAssistant professor, Department of Biochemistry and Molecular Biophysics, Columbia University, and co-author of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution”  

  • Hank GreelyDirector, Center for Law and the Biosciences; Chair of the Steering Committee of the Center for Biomedical Ethics; and Director, Stanford Program in Neuroscience and Society

Segments:
Part 1: Paul Davies / Genetic Messages
Part 2: Yin Shen / Dark Genome
Part 3: Sam Sternberg / Using CRISPR
Part 4: Hank Greely / Unintended Consequences

Descripción en español

Originally aired November 6, 2017

Podcast also available on PocketCasts, SoundCloud, Spotify, Google Podcasts, Apple Podcasts, and RSS.

2026 Webby Award Nominee
for our three part series on the 20th anniversary of Hurricane Katrina

Big Picture Science is an immersive radio show and podcast that reveals the unexpected connections in science.

Our Skeptic Check episodes take a critical look at extraordinary science claims and pseudoscience.

Don’t settle for a science snapshot. Get the big picture. 

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Molly Bentley Executive Producer and Co-Host, Big Picture Science  

Seth Shostak Producer and Co-Host, Big Picture Science
Senior Astronomer, SETI Institute

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